Genetic variations of nucleoprotein gene of influenza A viruses isolated from swine in Thailand.

ABSTRACT:

Background

Influenza A virus causes severe disease in both humans and animals and thus, has a considerably impact on economy and public health. In this study, the genetic variations of the nucleoprotein (NP) gene of influenza viruses recovered from swine in Thailand were determined.

Results

Twelve influenza A virus specimens were isolated from Thai swine. All samples were subjected to nucleotide sequencing of the complete NP gene. Phylogenetic analysis was conducted by comparing the NP gene of swine influenza viruses with that of seasonal and pandemic human viruses and highly pathogenic avian viruses from Thailand (n = 77). Phylogenetic analysis showed that the NP gene from different host species clustered in distinct host specific lineages. The NP gene of swine influenza vi

SUBMITTER: Thippamom N 

PROVIDER: S-EPMC2924863 | biostudies-literature | 2010 Aug

REPOSITORIES: biostudies-literature