Ontology highlight
ABSTRACT:
SUBMITTER: McDaniell R
PROVIDER: S-EPMC2929018 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
Science (New York, N.Y.) 20100318 5975
The extent to which variation in chromatin structure and transcription factor binding may influence gene expression, and thus underlie or contribute to variation in phenotype, is unknown. To address this question, we cataloged both individual-to-individual variation and differences between homologous chromosomes within the same individual (allele-specific variation) in chromatin structure and transcription factor binding in lymphoblastoid cells derived from individuals of geographically diverse ...[more]