Gold(I)-catalyzed amination of allylic alcohols with cyclic ureas and related nucleophiles.

ABSTRACT: A 1:1 mixture of [P(t-Bu)(2)-o-biphenyl]AuCl and AgSbF(6) catalyzes the intermolecular amination of allylic alcohols with 1-methylimidazolidin-2-one and related nucleophiles that, in the case of gamma-unsubstituted or gamma-methyl-substituted allylic alcohols, occurs with high gamma-regioselectivity and syn-stereoselectivity.

SUBMITTER: Mukherjee P 

PROVIDER: S-EPMC2929168 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature