Fatty acid interactions with genetic polymorphisms for cardiovascular disease.

ABSTRACT:

Purpose of review

The number of studies investigating interactions between genes and nutrients for cardiovascular disease continues to grow, and holds tremendous potential for reducing disease risk at the level of the individual genotype. However, understanding the limitations and challenges of interaction studies, whether of observational or interventional design, is essential for critical evaluation of these studies.

Recent findings

Nutrient-gene interactions for cardiovascular disease both parallel and extend nutrition studies, encompassing both traditional and novel cardiovascular risk factors. Fatty acid quality, lipid metabolism, inflammation, postprandial metabolism, fatty liver and macronutrient-gene interactions for obesity and metabolic syndrome represent a subset

SUBMITTER: Smith CE 

PROVIDER: S-EPMC2930761 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature