Cu(I)-catalyzed regioselective diamination of conjugated dienes via dual mechanistic pathways.

ABSTRACT: This paper describes the Cu(I)-catalyzed regioselective diamination of conjugated dienes using di-tert-butyldiaziridinone as nitrogen source. The internal diamination and terminal diamination likely proceed via two mechanistic pathways. Various dienes can be efficiently diaminated at the internal double bonds with high regio- and diasteroselectivity in good yield using inexpensive CuBr as catalyst.

SUBMITTER: Zhao B 

PROVIDER: S-EPMC2933359 | biostudies-literature | 2010 Aug

REPOSITORIES: biostudies-literature