PCAS--a precomputed proteome annotation database resource.

ABSTRACT:

Background

Many model proteomes or "complete" sets of proteins of given organisms are now publicly available. Much effort has been invested in computational annotation of those "draft" proteomes. Motif or domain based algorithms play a pivotal role in functional classification of proteins. Employing most available computational algorithms, mainly motif or domain recognition algorithms, we set up to develop an online proteome annotation system with integrated proteome annotation data to complement existing resources.

Results

We report here the development of PCAS (ProteinCentric Annotation System) as an online resource of pre-computed proteome annotation data. We applied most available motif or domain databases and their analysis methods, including hmmpfam search of HMMs in P

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC293463 | biostudies-literature | 2003 Nov

REPOSITORIES: biostudies-literature