Ethmoid histopathology does not predict olfactory outcomes after endoscopic sinus surgery.

ABSTRACT:

Background

Histological inflammation correlates with the degree of baseline olfactory dysfunction in patients with chronic rhinosinusitis (CRS); however, factors associated with improvement in olfactory status after endoscopic sinus surgery (ESS) remain elusive. Our purpose was to compare histopathological findings in CRS patients with olfactory loss and evaluate whether inflammatory markers can predict long-term olfactory improvement after ESS.

Methods

Adult (> or = 18 years) patients with CRS were prospectively enrolled after electing ESS due to failed medical management. Mucosal tissue specimens were collected at the time of surgery and underwent pathological review in a blinded fashion. Subjects completed the 40-item Smell Identification Test (SIT) preoperatively and at

SUBMITTER: Soler ZM 

PROVIDER: S-EPMC2936485 | biostudies-literature | 2010 Jul-Aug

REPOSITORIES: biostudies-literature