Familial transmission and heritability of childhood disruptive disorders.

ABSTRACT:

Objective

There is substantial evidence of a link between parental substance use disorders and antisocial behavior and childhood disruptive disorders in offspring, but it is unclear whether this transmission is specific to particular disorders or if a general liability accounts for familial resemblance. The authors examined whether the association between parental externalizing disorders and childhood disruptive disorders in preadolescent offspring is a result of the transmission of general or disorder-specific liabilities and estimated the genetic and environmental contributions to variation in these general and specific liability indicators.

Method

Participants were 1,069 families consisting of 11-year-old twins and their biological mother and father. Structural equation m

SUBMITTER: Bornovalova MA 

PROVIDER: S-EPMC2936682 | biostudies-literature | 2010 Sep

REPOSITORIES: biostudies-literature