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Room-temperature aromatization of tetrahydro-?-carbolines by 2-iodoxybenzoic acid: utility in a total synthesis of eudistomin U.

ABSTRACT: 2-Iodoxybenzoic acid is a convenient reagent for the dehydrogenation of tetrahydro-?-carbolines to their aromatic forms under mild conditions. The utility of the method was demonstrated in a total synthesis of the marine indole alkaloid eudistomin U.

SUBMITTER: Panarese JD

PROVIDER: S-EPMC2937063 | biostudies-literature | 2010 Sep

REPOSITORIES: biostudies-literature

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Room-temperature aromatization of tetrahydro-β-carbolines by 2-iodoxybenzoic acid: utility in a total synthesis of eudistomin U.

Panarese Joseph D JD Waters Stephen P SP

Organic letters 20100901 18

2-Iodoxybenzoic acid is a convenient reagent for the dehydrogenation of tetrahydro-β-carbolines to their aromatic forms under mild conditions. The utility of the method was demonstrated in a total synthesis of the marine indole alkaloid eudistomin U. ...[more]

PMID: 20715768

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