Thermostability of subpopulations of H2N3 influenza virus isolates from mallard ducks.

ABSTRACT: Maintenance of avian influenza virus in waterfowl populations requires that virions remain infectious while in the environment. Temperature has been shown to negatively correlate with persistence time, which is the duration for which virions are infectious. However, thermostability can vary between isolates regardless of subtype, and it is not known whether this variation occurs when host and geographic location of isolation are controlled. In this study, we analyzed the thermostabilities of 7 H2N3 viruses isolated from mallard ducks in Alberta, Canada. Virus samples were incubated at 37 degrees C and 55 degrees C, and infectivity titers were calculated at different time points. Based on the rate of infectivity inactivation at 37 degrees C, isolates could be grouped into either a thermosen

SUBMITTER: Negovetich NJ 

PROVIDER: S-EPMC2937660 | biostudies-literature | 2010 Sep

REPOSITORIES: biostudies-literature