Outcome and prognostic factors of desmoplastic medulloblastoma treated within a multidisciplinary treatment concept.

ABSTRACT:

Background

Desmoplasia in medulloblastoma is often diagnosed in adult patients and was repeatedly associated with improved results. Today, all medulloblastoma patients receive intensive multimodal treatment including surgery, radiotherapy and chemotherapy. This study was set up to investigate treatment outcome and prognostic factors after radiation therapy in patients with desmoplastic medulloblastomas.

Methods

Twenty patients treated for desmoplastic medulloblastoma in the Department of Radiation Oncology at the University of Heidelberg between 1984 and 2007 were included. Data were collected retrospectively. Tumor resection was performed in all patients. All patients underwent postsurgical radiotherapy (RT). Two patients underwent whole brain radiotherapy (WBRT), and 18 pa

SUBMITTER: Rieken S 

PROVIDER: S-EPMC2939548 | biostudies-literature | 2010 Aug

REPOSITORIES: biostudies-literature