Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs.

ABSTRACT:

Background

Regeneration is the ability of an organism to rebuild a body part that has been damaged or amputated, and can be studied at the molecular level using model organisms. Drosophila imaginal discs, which are the larval primordia of adult cuticular structures, are capable of undergoing regenerative growth after transplantation and in vivo culture into the adult abdomen.

Results

Using expression profile analyses, we studied the regenerative behaviour of wing discs at 0, 24 and 72 hours after fragmentation and implantation into adult females. Based on expression level, we generated a catalogue of genes with putative role in wing disc regeneration, identifying four classes: 1) genes with differential expression within the first 24 hours; 2) genes with differential express

SUBMITTER: Blanco E 

PROVIDER: S-EPMC2939566 | biostudies-literature | 2010 Sep

REPOSITORIES: biostudies-literature