Scale to predict survival after surgery for recurrent glioblastoma multiforme.

ABSTRACT:

Purpose

Despite initial treatment with surgical resection, radiotherapy, and chemotherapy, glioblastoma multiforme (GBM) virtually always recurs. Surgery is sometimes recommended to treat recurrence. In this study, we sought to devise a preoperative scale that predicts survival after surgery for recurrent glioblastoma multiforme.

Patients and methods

The preoperative clinical and radiographic data of 34 patients who underwent re-operation of recurrent GBM tumors were analyzed using Kaplan-Meier survival analysis and Cox proportional hazards regression modeling. The factors associated with decreased postoperative survival (P < .05) were used to devise a prognostic scale which was validated with a separate cohort of 109 patients.

Results

The factors associated with poor

SUBMITTER: Park JK 

PROVIDER: S-EPMC2940401 | biostudies-literature | 2010 Aug

REPOSITORIES: biostudies-literature