Dynamics of the multiplicity of cellular infection in a plant virus.

ABSTRACT: Recombination, complementation and competition profoundly influence virus evolution and epidemiology. Since viruses are intracellular parasites, the basic parameter determining the potential for such interactions is the multiplicity of cellular infection (cellular MOI), i.e. the number of viral genome units that effectively infect a cell. The cellular MOI values that prevail in host organisms have rarely been investigated, and whether they remain constant or change widely during host invasion is totally unknown. Here, we fill this experimental gap by presenting the first detailed analysis of the dynamics of the cellular MOI during colonization of a host plant by a virus. Our results reveal ample variations between different leaf levels during the course of infection, with values starting c

SUBMITTER: Gutierrez S 

PROVIDER: S-EPMC2940754 | biostudies-literature | 2010 Sep

REPOSITORIES: biostudies-literature