Quantification of vestibular-induced eye movements in zebrafish larvae.

ABSTRACT:

Background

Vestibular reflexes coordinate movements or sensory input with changes in body or head position. Vestibular-evoked responses that involve the extraocular muscles include the vestibulo-ocular reflex (VOR), a compensatory eye movement to stabilize retinal images. Although an angular VOR attributable to semicircular canal stimulation was reported to be absent in free-swimming zebrafish larvae, recent studies reveal that vestibular-induced eye movements can be evoked in zebrafish larvae by both static tilts and dynamic rotations that tilt the head with respect to gravity.

Results

We have determined herein the basis of sensitivity of the larval eye movements with respect to vestibular stimulus, developmental stage, and sensory receptors of the inner ear. For our experi

SUBMITTER: Mo W 

PROVIDER: S-EPMC2941499 | biostudies-literature | 2010 Sep

REPOSITORIES: biostudies-literature