Predictors and moderators of treatment outcome in the Pediatric Obsessive Compulsive Treatment Study (POTS I).

ABSTRACT:

Objective

To identify predictors and moderators of outcome in the first Pediatric OCD Treatment Study (POTS I) among youth (N = 112) randomly assigned to sertraline, cognitive behavioral therapy (CBT), both sertraline and CBT (COMB), or a pill placebo.

Method

Potential baseline predictors and moderators were identified by literature review. The outcome measure was an adjusted week 12 predicted score for the Children's Yale Brown Obsessive Compulsive Scale (CY-BOCS). Main and interactive effects of treatment condition and each candidate predictor or moderator variable were examined using a general linear model on the adjusted predicted week 12 CY-BOCS scores.

Results

Youth with lower obsessive-compulsive disorder (OCD) severity, less OCD-related functional impairment,

SUBMITTER: Garcia AM 

PROVIDER: S-EPMC2943932 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature