A framework for oligonucleotide microarray preprocessing.

ABSTRACT:

Motivation

The availability of flexible open source software for the analysis of gene expression raw level data has greatly facilitated the development of widely used preprocessing methods for these technologies. However, the expansion of microarray applications has exposed the limitation of existing tools.

Results

We developed the oligo package to provide a more general solution that supports a wide range of applications. The package is based on the BioConductor principles of transparency, reproducibility and efficiency of development. It extends the existing tools and leverages existing code for visualization, accessing data and widely used preprocessing routines. The oligo package implements a unified paradigm for preprocessing data and interfaces with other BioConductor

SUBMITTER: Carvalho BS 

PROVIDER: S-EPMC2944196 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature