The PpaA/AerR regulators of photosynthesis gene expression from anoxygenic phototrophic proteobacteria contain heme-binding SCHIC domains.

ABSTRACT: The SCHIC domain of the B12-binding domain family present in the Rhodobacter sphaeroides AppA protein binds heme and senses oxygen. Here we show that the predicted SCHIC domain PpaA/AerR regulators also bind heme and respond to oxygen in vitro, despite their low sequence identity with AppA.

SUBMITTER: Moskvin OV 

PROVIDER: S-EPMC2944501 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature