Racial differences in the association between sex hormone-binding globulin and adiposity in premenopausal women: the BioCycle study.

ABSTRACT:

Objective

To assess the associations between measures of adiposity and sex hormone- binding globulin (SHBG) and to evaluate whether such associations differ by race.

Research design and methods

Adiposity was measured by anthropometry and dual-energy X-ray absorptiometry among women (146 white, 50 black, and 25 Asian) aged 18-44 years in the BioCycle study. SHBG was repeatedly measured over one to two menstrual cycles. The ratio of trunkal to leg fat (T/L) was used to assess upper to lower body adiposity.

Results

Among whites, all adiposity measures were significantly and inversely associated with SHBG. Among blacks, BMI (β = -0.032), waist circumference (β = -0.016), and T/L (β = -0.033) were significantly associated with SHBG, whereas total and trunkal fat were not (

SUBMITTER: Yeung EH 

PROVIDER: S-EPMC2945174 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature