Mammographic density change with 1 year of aerobic exercise among postmenopausal women: a randomized controlled trial.

ABSTRACT:

Background

The Alberta Physical Activity and Breast Cancer Prevention (ALPHA) Trial examined the influence of aerobic exercise on biological factors that are associated with breast cancer risk. Mammographic density, a secondary outcome, is reported here.

Methods

The ALPHA Trial was a parallel group randomized controlled trial conducted between May 2003 and July 2007. Postmenopausal, sedentary women ages 50 to 74 years (n = 320) were evenly randomized to aerobic exercise (45 minutes, 5 days per week) or control (usual life-style) for 1 year. Dense fibroglandular tissue and nondense fatty tissue were measured from mammograms at baseline and 1 year using computer-assisted thresholding software for area measurements and a new technique that relies on the calibration of mammograp

SUBMITTER: Woolcott CG 

PROVIDER: S-EPMC2945907 | biostudies-literature | 2010 Apr

REPOSITORIES: biostudies-literature