Adverse effects of extra-articular corticosteroid injections: a systematic review.

ABSTRACT:

Background

To estimate the occurrence and type of adverse effects after application of an extra-articular (soft tissue) corticosteroid injection.

Methods

A systematic review of the literature was made based on a PubMed and Embase search covering the period 1956 to January 2010. Case reports were included, as were prospective and retrospective studies that reported adverse events of corticosteroid injection. All clinical trials which used extra-articular corticosteroid injections were examined. We divided the reported adverse events into major (defined as those needing intervention or not disappearing) and minor ones (transient, not requiring intervention).

Results

The search yielded 87 relevant studies:44 case reports, 37 prospective studies and 6 retrospective studie

SUBMITTER: Brinks A 

PROVIDER: S-EPMC2945953 | biostudies-literature | 2010 Sep

REPOSITORIES: biostudies-literature