Aziridinomitosanes via lactam cyclization.

ABSTRACT: Aziridinomitosane ketones 4 and 24 are accessed by internal acyl anion equivalent-lactam cyclization of 29 in a convergent route. The key aziridinolactam 6 is prepared by tin-lithium exchange via the lithiated aziridine 11.

SUBMITTER: Wiedner SD 

PROVIDER: S-EPMC2946824 | biostudies-literature | 2010 Sep

REPOSITORIES: biostudies-literature