Idiopathic systemic capillary leak syndrome (Clarkson's disease): the Mayo clinic experience.

ABSTRACT:

Objective

To determine clinical features, natural history, and outcome of a well-defined cohort of 25 consecutive patients with idiopathic systemic capillary leak syndrome (SCLS) evaluated at a tertiary care center.

Patients and methods

Records of patients diagnosed as having SCLS from November 1, 1981, through April 30, 2008, were reviewed. Descriptive statistics were used to analyze patient demographics, clinical features, complications, and therapeutic interventions.

Results

Of the 34 patients whose records were reviewed, 25 fulfilled all diagnostic criteria for SCLS. The median age at diagnosis of SCLS was 44 years. Median follow-up of surviving patients was 4.9 years, and median time to diagnosis from symptom onset was 1.1 years (interquartile range, 0.5-4.1 year

SUBMITTER: Kapoor P 

PROVIDER: S-EPMC2947962 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature