Wide-field motion integration in fly VS cells: insights from an inverse approach.

ABSTRACT: Fly lobula plate tangential cells are known to perform wide-field motion integration. It is assumed that the shape of these neurons, and in particular the shape of the subclass of VS cells, is responsible for this type of computation. We employed an inverse approach to investigate the morphology-function relationship underlying wide-field motion integration in VS cells. In the inverse approach detailed, model neurons are optimized to perform a predefined computation: here, wide-field motion integration. We embedded the model neurons to be optimized in a biologically plausible model of fly motion detection to provide realistic inputs, and subsequently optimized model neuron with and without active conductances (g(Na), g(K), g(K(Na))) along their dendrites to perform this computation. We fou

SUBMITTER: Torben-Nielsen B 

PROVIDER: S-EPMC2947983 | biostudies-literature | 2010 Sep

REPOSITORIES: biostudies-literature