Toll-like receptor 3 in liver diseases.
Ontology highlight
ABSTRACT:
SUBMITTER: Yin S
PROVIDER: S-EPMC2948910 | biostudies-literature | 2010
REPOSITORIES: biostudies-literature
Publications
Toll-like receptor 3 in liver diseases.
Gastroenterology research and practice 20100923
Toll-like receptor 3 (TLR3) is a member of the TLR family that can recognize double-stranded RNA (dsRNA), playing an important role in antiviral immunity. Recent studies have shown that TLR3 is also expressed on parenchymal and nonparenchymal cells in the liver as well as on several types of immune cells. In this review, we summarize the role of TLR3 in liver injury, inflammation, regeneration, and liver fibrosis, and discuss the implication of TLR3 in the pathogenesis of human liver diseases in ...[more]
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