Pulmonary function abnormalities in HIV-infected patients during the current antiretroviral therapy era.

ABSTRACT:

Rationale

Before the introduction of combination antiretroviral (ARV) therapy, patients infected with HIV had an increased prevalence of respiratory symptoms and lung function abnormalities. The prevalence and exact phenotype of pulmonary abnormalities in the current era are unknown. In addition, these abnormalities may be underdiagnosed.

Objectives

Our objective was to determine the current burden of respiratory symptoms, pulmonary function abnormalities, and associated risk factors in individuals infected with HIV.

Methods

Cross-sectional analysis of 167 participants infected with HIV who underwent pulmonary function testing.

Measurements and main results

Respiratory symptoms were present in 47.3% of participants and associated with intravenous drug use (odds

SUBMITTER: Gingo MR 

PROVIDER: S-EPMC2949404 | biostudies-literature | 2010 Sep

REPOSITORIES: biostudies-literature