Cognitive performance and leukocyte telomere length in two narrow age-range cohorts: a population study.

ABSTRACT:

Background

Cognitive function and telomere length both decline with age. A correlation between these two measures would suggest that they may be influenced by the same underlying age-related biological process. Several studies suggest telomere length may be positively correlated with cognitive performance but the evidence is equivocal. In this report, the relationships between telomere length and cognitive performance at Wave 2 and cognitive change from Wave 1 to Wave 2 are assessed in two narrow age-range population cohorts.

Methods

We tested the hypothesis that leukocyte telomere length correlates positively with cognitive performance and cognitive decline in two community cohorts of middle-aged (n = 351, 44-49 years) and older (n = 295, 64-70 years) adults, who participat

SUBMITTER: Mather KA 

PROVIDER: S-EPMC2949672 | biostudies-literature | 2010 Sep

REPOSITORIES: biostudies-literature