The evolutionary trajectory of mitochondrial carrier family during metazoan evolution.

ABSTRACT:

Background

Exploring metabolic evolution is a way to understand metabolic complexity. The substrate transport of mitochondrial carrier family (MCF) influences direct metabolic activities, making it possible to understand indirectly metabolic evolution from the evolution of substrate transport of MCF. However, the evolutionary study of substrate transport of MCF does not mean that all the concrete structures of mitochondrial carriers (MCs) must first be gained.

Results

Here we studied the alternation of MCF structure and potential correlated functions of MCF during metazoan evolution. The data analysis indicates that the types of substrates transported by MCF as a whole were maintained during metazoan evolution. However, the size of the substrates transported by members of MC

SUBMITTER: Gong M 

PROVIDER: S-EPMC2949871 | biostudies-literature | 2010 Sep

REPOSITORIES: biostudies-literature