Weight and metabolic outcomes after 2 years on a low-carbohydrate versus low-fat diet: a randomized trial.

ABSTRACT:

Background

Previous studies comparing low-carbohydrate and low-fat diets have not included a comprehensive behavioral treatment, resulting in suboptimal weight loss.

Objective

To evaluate the effects of 2-year treatment with a low-carbohydrate or low-fat diet, each of which was combined with a comprehensive lifestyle modification program.

Design

Randomized parallel-group trial. (ClinicalTrials.gov registration number: NCT00143936)

Setting

3 academic medical centers.

Patients

307 participants with a mean age of 45.5 years (SD, 9.7 years) and mean body mass index of 36.1 kg/m(2) (SD, 3.5 kg/m(2)).

Intervention

A low-carbohydrate diet, which consisted of limited carbohydrate intake (20 g/d for 3 months) in the form of low-glycemic index vegetables wi

SUBMITTER: Foster GD 

PROVIDER: S-EPMC2949959 | biostudies-literature | 2010 Aug

REPOSITORIES: biostudies-literature