Effectiveness of earlier antenatal screening for sickle cell disease and thalassaemia in primary care: cluster randomised trial.

ABSTRACT:

Objective

To evaluate the effectiveness of offering antenatal screening for sickle cell disease and thalassaemia in primary care as a way of facilitating earlier uptake of screening.

Design

Partial factorial cluster randomised controlled trial.

Setting

25 UK general practices from deprived inner city areas.

Participants

Anonymised data on all pregnant women attending participating practices during a six month period before randomisation and a seven month period after randomisation. This included 1708 eligible women.

Intervention

Practices were randomised to three groups for seven months: parallel testing in general practice (tests for sickle cell disease and thalassaemia offered to both parents when pregnancy was first reported); sequential testing in ge

SUBMITTER: Dormandy E 

PROVIDER: S-EPMC2950261 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature