Temporal frequency of subthreshold oscillations scales with entorhinal grid cell field spacing.

ABSTRACT: Grid cells in layer II of rat entorhinal cortex fire to spatial locations in a repeating hexagonal grid, with smaller spacing between grid fields for neurons in more dorsal anatomical locations. Data from in vitro whole-cell patch recordings showed differences in frequency of subthreshold membrane potential oscillations in entorhinal neurons that correspond to different positions along the dorsal-to-ventral axis, supporting a model of physiological mechanisms for grid cell responses.

SUBMITTER: Giocomo LM 

PROVIDER: S-EPMC2950607 | biostudies-literature | 2007 Mar

REPOSITORIES: biostudies-literature