Ontology highlight
ABSTRACT:
SUBMITTER: Yan W
PROVIDER: S-EPMC2951216 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
The Journal of biological chemistry 20100730 41
Spermatogenesis is a complex process through which male germ line stem cells undergo a multi-step differentiation program and sequentially become spermatogonia, spermatocytes, spermatids, and eventually spermatozoa. In this process, transcription factors act as switches that precisely regulate the expression of genes that in turn control the developmental program of male germ cells. Transcription factors identified to be essential for normal haploid gene expression all display transcription-acti ...[more]