Differences in allergic sensitization by self-reported race and genetic ancestry.

ABSTRACT:

Background

Many allergic conditions occur more frequently in African American patients when compared with white patients; however, it is not known whether this represents genetic predisposition or disparate environmental exposures.

Objective

We sought to assess the relationship of self-reported race and genetic ancestry to allergic sensitization.

Methods

We included 601 women enrolled in a population-based cohort study whose self-reported race was African American or white. Genetic ancestry was estimated by using markers that differentiate West African and European ancestry. We assessed the relationship between allergic sensitization (defined as > or =1 allergen-specific IgE results) and both self-reported race and genetic ancestry. Regression models adjusted for soci

SUBMITTER: Yang JJ 

PROVIDER: S-EPMC2951327 | biostudies-literature | 2008 Oct

REPOSITORIES: biostudies-literature