Nearest-neighbor classifier as a tool for classification of protein families.

ABSTRACT: Knowledge about protein function is essential in understanding the biological processes. A specific class or family of protein shares common structural and chemical properties amongst its member sequences. The set of properties that display its unique characteristics for clearly classifying a protein sequence into its corresponding protein family needs to be studied. Our study of these important properties conducted on four major classes of proteins namely Globins, Homeoboxes, Heat Shock proteins (HSP) and Kinase have shown that frequency of twenty naturally occurring amino acids, hydrophobic content of protein, molecular weight of protein, isoelectric point of protein, secondary structure composition of amino acid residues as helices, coils and sheets and the composition of helices, coils

SUBMITTER: Chaurasiya M 

PROVIDER: S-EPMC2951634 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature