Ontology highlight
ABSTRACT:
SUBMITTER: Asif SM
PROVIDER: S-EPMC2951718 | biostudies-literature | 2009 Dec
REPOSITORIES: biostudies-literature
Bioinformation 20091231 6
Mycobacterium tuberculosis is the causative agent of the disease, tuberculosis and H37Rv is the most studied clinical strain. We use comparative genome analysis of Mycobacterium tuberculosis H37Rv and human for the identification of potential targets dataset. We used DEG (Database of Essential Genes) to identify essential genes in the H37Rv strain. The analysis shows that 628 of the 3989 genes in Mycobacterium tuberculosis H37Rv were found to be essential of which 324 genes lack similarity to th ...[more]