Iron-catalyzed heterocycle and arene deprotonative alkylation.

ABSTRACT: A method for iron-catalyzed deprotonative alkylation of arene C-H bonds by alkyl iodides and bromides has been developed. In the presence of an amide base, both primary and secondary alkyl halides can be coupled with furans, thiophenes, pyridine derivatives, and some electron-withdrawing-group containing arenes.

SUBMITTER: Tran LD 

PROVIDER: S-EPMC2952416 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature