Ligands in crystal structures that aid in functional characterization.

ABSTRACT: Liganded structures can be instrumental in assigning function to uncharacterized proteins by revealing active sites, conserved residues, binding motifs, and substrate specificity. This introduction provides an overview and commentary on the value of liganded structures emerging from the JCSG structural genomics initiative.

SUBMITTER: Speers AE 

PROVIDER: S-EPMC2954220 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature