Effects of Concord grape juice on ambulatory blood pressure in prehypertension and stage 1 hypertension.

ABSTRACT:

Background

Consumption of flavonoid-containing foods may be useful for the management of hypertension.

Objective

We investigated whether 100% Concord grape juice lowers blood pressure in patients with prehypertension and stage 1 hypertension.

Design

We conducted a double-blind crossover study to compare the effects of grape juice (7 mL · kg⁻¹ · d⁻¹) and matched placebo beverage on 24-h ambulatory blood pressure, stress-induced changes in blood pressure, and biochemical profile. Participants consumed each beverage for 8 wk with a 4-wk rest period between beverages. They ceased consumption of grapes and other flavonoid-containing beverages throughout the study.

Results

We enrolled 64 otherwise healthy patients taking no antihypertensive medications (31% women, 42

SUBMITTER: Dohadwala MM 

PROVIDER: S-EPMC2954442 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature