Caffeine consumption during pregnancy and risk of preterm birth: a meta-analysis.

ABSTRACT:

Background

The effect of caffeine intake during pregnancy on the risk of preterm delivery has been studied for the past 3 decades with inconsistent results.

Objective

We performed a meta-analysis examining the association between caffeine consumption during pregnancy and risk of preterm birth.

Design

We searched MEDLINE and EMBASE articles published between 1966 and July 2010, cross-referenced reference lists of the retrieved articles, and identified 15 cohort and 7 case-control studies that met inclusion criteria for this meta-analysis.

Results

The combined odds ratios (ORs) obtained by using fixed-effects models for cohort studies were 1.11 (95% CI: 0.96, 1.28), 1.10 (95% CI: 1.01, 1.19), and 1.08 (95% CI: 0.93, 1.27) for risk of preterm birth comparing the h

SUBMITTER: Maslova E 

PROVIDER: S-EPMC2954446 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature