Statins and clinical outcome of acute ischemic stroke: a systematic review.

ABSTRACT:

Background

Statin therapy is considered an effective measure for the prevention of ischemic stroke. Several recent studies have indicated that treatment with statins, prior to the onset of acute ischemic stroke, may also substantially reduce the severity of stroke and the degree of patient disability. The purpose of the present review is to systematically evaluate the effectiveness of statin pretreatment on functional outcome of acute ischemic stroke and to assess potential adverse events associated with statin use.

Methods

Relevant articles on the role of statins in acute ischemic stroke were identified via MEDLINE/PubMed, EMBASE, CENTRAL, and by manual searches of the references of identified papers. Clinical studies (most were prospective cohort studies) assessing statin

SUBMITTER: Lakhan SE 

PROVIDER: S-EPMC2954982 | biostudies-literature | 2010 Sep

REPOSITORIES: biostudies-literature