Design of the xylitol for adult caries trial (X-ACT).

ABSTRACT:

Background

Dental caries incidence in adults is similar to that in children and adolescents, but few caries preventive agents have been evaluated for effectiveness in adults populations. In addition, dentists direct fewer preventive services to their adult patients. Xylitol, an over-the-counter sweetener, has shown some potential as a caries preventive agent, but the evidence for its effectiveness is not yet conclusive and is based largely on studies in child populations.

Methods/design

X-ACT is a three-year, multi-center, placebo controlled, double-blind, randomized clinical trial that tests the effects of daily use of xylitol lozenges versus placebo lozenges on the prevention of adult caries. The trial has randomized 691 participants (ages 21-80) to the two arms. The prima

SUBMITTER: Bader JD 

PROVIDER: S-EPMC2955560 | biostudies-literature | 2010 Sep

REPOSITORIES: biostudies-literature