Repeated courses of antenatal corticosteroids: are there effects on the infant's auditory brainstem responses?

ABSTRACT: Our objective was to assess the effects of repeated antenatal corticosteroid treatments on the neonatal auditory brainstem response (ABR), a sensitive measure of neonatal brain maturity and auditory function. To achieve this, we performed and blindly evaluated neonatal ABRs on a subset of infants delivering within a multicenter randomized placebo-controlled clinical trial comparing single versus repeated courses of antenatal corticosteroid treatments for women at 23-31 weeks gestation who remained at increased risk for preterm birth. The women were randomly assigned to either the single or the repeated antenatal corticosteroid treatment group. Women in the repeated antenatal corticosteroid group received weekly antenatal corticosteroid treatments until 34 weeks gestation or until they reac

SUBMITTER: Church MW 

PROVIDER: S-EPMC2955992 | biostudies-literature | 2010 Nov-Dec

REPOSITORIES: biostudies-literature