Stimulant-responsive and stimulant-refractory aggressive behavior among children with ADHD.

ABSTRACT:

Objectives

The objective of this study was to examine factors that are associated with aggression that is responsive versus refractory to individualized optimization of stimulant monotherapy among children with attention-deficit/hyperactivity disorder (ADHD).

Methods

Children who were aged 6 to 13 years and had ADHD, either oppositional defiant disorder or conduct disorder, significant aggressive behavior, and a history of insufficient response to stimulants completed an open stimulant monotherapy optimization protocol. Stimulant titration with weekly assessments of behavior and tolerability identified an optimal regimen for each child. Families also received behavioral therapy. Parents completed the Retrospective-Modified Overt Aggression Scale (R-MOAS) at each visit. Child

SUBMITTER: Blader JC 

PROVIDER: S-EPMC2956067 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature