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(E)-3-(4-Hydr-oxy-3-methoxy-benzyl-idene)-4-(4-hydroxy-phen-yl)pyrrolidin-2-one.

ABSTRACT: The title compound, C(18)H(17)NO(4), was isolated from an ethanol extract of Ophiopogon japonicus. The dihedral angle between the 4-hydroxy-3-methoxyphenyl ring and the pyrrolidine ring is 17.4 (1)°. The 4-hydroxyphenyl ring makes a dihedral angle of 69.74 (6)° with the least-squares plane through the 4-hydroxy-3-methoxyphenyl ring and the pyrrolidine ring. The conformation of the pyrrolidine fragment is similar to a T-form. The crystal structure is stabilized by inter-molecular N-H⋯O and O-H⋯O hydrogen bonds.

SUBMITTER: Zhou YF

PROVIDER: S-EPMC2961252 | biostudies-literature | 2008 Apr

REPOSITORIES: biostudies-literature

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(E)-3-(4-Hydr-oxy-3-methoxy-benzyl-idene)-4-(4-hydroxy-phen-yl)pyrrolidin-2-one.

Zhou Yi-Feng YF Wang Xiao-Bing XB Qi Jin J Yu Bo-Yang BY

Acta crystallographica. Section E, Structure reports online 20080410 Pt 5

The title compound, C(18)H(17)NO(4), was isolated from an ethanol extract of Ophiopogon japonicus. The dihedral angle between the 4-hydroxy-3-methoxyphenyl ring and the pyrrolidine ring is 17.4 (1)°. The 4-hydroxyphenyl ring makes a dihedral angle of 69.74 (6)° with the least-squares plane through the 4-hydroxy-3-methoxyphenyl ring and the pyrrolidine ring. The conformation of the pyrrolidine fragment is similar to a T-form. The crystal structure is stabilized by inter-molecular N-H⋯O and O-H⋯O ...[more]

PMID: 21202304

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