Using neutron protein crystallography to understand enzyme mechanisms.

ABSTRACT: A description is given of the results of neutron diffraction studies of the structures of four different metal-ion complexes of deuterated D-xylose isomerase. These represent four stages in the progression of the biochemical catalytic action of this enzyme. Analyses of the structural changes observed between the various three-dimensional structures lead to some insight into the mechanism of action of this enzyme.

SUBMITTER: Glusker JP 

PROVIDER: S-EPMC2967424 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature