Outcome selection and role of patient reported outcomes in contemporary cardiovascular trials: systematic review.

ABSTRACT:

Objectives

To systematically assess the type of outcomes selected and the prevalence of patient reported outcomes in contemporary cardiovascular trials and to quantify any misuse or underuse of patient reported outcomes using a specially developed tool that would allow estimation of the relevance of such outcomes to clinical decision making.

Design

Systematic review.

Data sources

Medline and Embase.

Study selection

Randomised controlled trials of the treatment for or prevention of cardiovascular disease published in 10 leading general medical and cardiology journals from January 2005 to December 2008.

Results

Primary outcomes were patient important (death, morbidity, or patient reported outcomes) in only 93 of 413 trials (23%, SE 2%), whereas another 92

SUBMITTER: Rahimi K 

PROVIDER: S-EPMC2967478 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature