1,2,3,4-Tetra-hydro-1,4-methano-naphthalene-2,3-diol.

ABSTRACT: The title compound, C(11)H(12)O(2), is an inter-mediate in the synthesis of Varenicline, a nicotinic receptor partial agonist used to treat smoking addiction. In the crystal structure, there is an intra-molecular O-H⋯O hydrogen bond that generates an S(5) ring motif. Inter-molecular O-H⋯O hydrogen bonds form centrosymmetric dimers and also link these dimers into chains along the a axis.

SUBMITTER: Xu J 

PROVIDER: S-EPMC2967988 | biostudies-literature | 2008 Dec

REPOSITORIES: biostudies-literature