2-[6,8-Dibromo-3-(4-hydroxy-cyclo-hexyl)-1,2,3,4-tetra-hydro-quinazolin-2-yl]-6-methoxy-phenol.

ABSTRACT: The title compound, C(21)H(24)Br(2)N(2)O(3), was synthesized by the condensation reaction of 3-methoxy-salicylaldehyde with 4-(2-amino-3,5-dibromo-benzyl-amino)cyclo-hexa-nol in a methanol solution. The dihedral angle between the two benzene rings is 76.4 (3)°. The cyclo-hexyl ring adopts a chair configuration. There is an intra-molecular O-H⋯N hydrogen bond which affects the solid state conformation of the mol-ecule. The crystal structure is stabilized by inter-molecular O-H⋯O hydrogen bonds, forming chains running along the b axis.

SUBMITTER: Wang ZG 

PROVIDER: S-EPMC2968568 | biostudies-literature | 2009 Feb

REPOSITORIES: biostudies-literature