(8S,9R,10S,11S,13S,14S,16S,17R)-4,4-Dichloro-16β-methyl-3,20-dioxo-17,21-bis-(propano-yloxy)-5β,8β-epoxy-pregna-1,9-diene.

ABSTRACT: The title compound, C(28)H(34)Cl(2)O(7), is a derivative of the glucocorticoid steroid beclomethasone dipropionate. It features an expoxide linkage [angle at oxygen = 96.6 (2)°]. The dichlorocyclohexenone ring adopts an envelope conformation, with the C atom bearing the two Cl substituents representing the flap. The dichloro-methyl C atom deviates by 0.471 (4) Å from the plane defined by the other five atoms, whose maximum r.m.s. deviation is 0.04 Å.

SUBMITTER: Ketuly KA 

PROVIDER: S-EPMC2970074 | biostudies-literature | 2009 Jul

REPOSITORIES: biostudies-literature