Microfabricated implants for applications in therapeutic delivery, tissue engineering, and biosensing.

ABSTRACT: By adapting microfabrication techniques originally developed in the microelectronics industry novel devices for drug delivery, tissue engineering and biosensing have been engineered for in vivo use. Implant microfabrication uses a broad range of techniques including photolithography, and micromachining to create devices with features ranging from 0.1 to hundreds of microns with high aspect ratios and precise features. Microfabrication offers device feature scale that is relevant to the tissues and cells to which they are applied, as well as offering ease of en masse fabrication, small device size, and facile incorporation of integrated circuit technology. Utilizing these methods, drug delivery applications have been developed for in vivo use through many delivery routes including intraveno

SUBMITTER: Ainslie KM 

PROVIDER: S-EPMC2970504 | biostudies-literature | 2008 Nov

REPOSITORIES: biostudies-literature